Table 1 Embedded adaptive interventions in the pilot SMARTÂ
Embedded Adaptive Intervention | First-stage intervention | Status | Second-stage intervention |
|---|---|---|---|
#1 | Nutrition counseling | Responder | Continue nutrition counseling |
Non-responder | Augment with metformin | ||
#2 | Nutrition counseling | Responder | Continue nutrition counseling |
Non-responder | Weight loss counseling | ||
#3 | Exercise counseling | Responder | Continue exercise counseling |
Non-responder | Augment with metformin | ||
#4 | Exercise counseling | Responder | Continue exercise counseling |
Non-responder | Weight loss counseling |