Skip to main content

Table 5 Secondary post-treatment outcomes by first-stage interventions

From: A pilot sequential multiple assignment randomized trial for developing a biobehavioral adaptive intervention to improve insulin sensitivity in patients with stage 1 obesity

Outcome

n

Baseline

n

Week 25

Mean change

95% CI

Cohen’s d

Weight, kg

20

      

 NC

20

100.08 (26.48)

17

97.91 (28.22)

 − 2.67 (3.49)

  

 EC

20

111.89 (29.28)

17

115.57 (32.54)

0.877 (3.24)

  

Between-group difference

    

3.55

1.47, 5.82

1.05

BMI, kg/m2

       

 NC

20

36.04 (7.68)

17

35.27 (7.99)

 − 0.98 (1.20)

  

 EC

20

39.09 (8.30)

 

40.61 (9.10)

0.28 (1.17)

  

Between-group difference

    

1.27

0.47, 2.06

1.07

Waist circumference, cm

       

 NC

20

108.98 (16.06)

17

109.26 (16.38)

 − 1.28 (5.46)

  

 EC

20

119.71 (20.13)

17

119.33 (25.80)

 − 1.70 (12.15)

  

Between-group difference

    

 − 0.71

 − 9.79, 5.52

 − 0.06

Body fat, %

       

 NC

20

44.87 (11.56)

17

43.00 (7.05)

 − 0.92 (2.76)

  

 EC

20

43.12 (9.23)

17

43.78 (9.88)

 − 0.80 (3.40)

  

Between-group difference

    

0.12

 − 2.04, 2.28

0.04

Lean body mass, %

       

 NC

20

57.04 (8.31)

17

57.15 (6.82)

1.11 (2.96)

  

 EC

20

54.57 (12.20)

17

55.80 (9.52)

3.10 (7.97)

  

FBG, mg/dL

       

 NC

20

97.10 (12.14)

17

93.24 (11.44)

 − 5.52 (9.74)

  

 EC

20

94.60 (9.39)

17

93.41 (12.35)

 − 0.94 (13.58)

  

Between-group difference

    

4.58

 − 3.66, 12.84

0.38

Cholesterol, mg/dL

       

 NC

20

186.60 (43.37)

17

187.10 (28.11)

 − 7.35 (38.96)

  

 EC

20

187.10 (28.11)

17

195.00 (50.83)

9.52 (34.21)

  

Between-group difference

    

16.88

 − 8.73, 42.49

0.46

LDL, mg/dL

       

 NC

20

113.10 (40.98)

17

113.82 (32.88)

 − 7.17 (34.25)

  

 EC

20

117.75 (26.03)

17

129.41 (42.96)

13.17 (30.22)

  

Between-group difference

    

20.35

 − 2.21, 42.92

0.63

HDL, mg/dL

       

 NC

20

56.10 (12.90)

17

52.35 (12.70)

 − 2.23 (5.84)

  

 EC

20

48.65 (11.29)

17

47.12 (9.74)

 − 2.17 (8.87)

  

Between-group difference

    

0.05

 − 5.19, 5.30

0.008

Triglycerides, mg/dL

       

 NC

20

93.15 (47.95)

17

96.71 (51.80)

 − 4.00 (30.28)

  

 EC

20

115.95 (41.21)

17

109.65 (60.63)

2.05 (33.32)

  

Between-group difference

    

6.05

 − 16.18, 28.30

0.20

Systolic BP mm Hg

       

 NC

20

137.60 (17.87)

17

138.98 (19.20)

 − 7.74 (18.55)

  

 EC

20

145.17 (21.97)

17

137.10 (15.71)

 − 2.78 (11.48)

  

Between-group difference

    

4.95

 − 5.82, 15.74

0.32

Diastolic BP, mm Hg

       

 NC

20

84.36 (13.97)

17

85.84 (8.55)

2.28 (10.45)

  

 EC

20

84.87 (9.39)

17

84.14 (10.51)

 − 1.64 (8.29)

 − 10.42, 2.65

 − 0.41

Between-group difference

       
  1. All data are presented as mean (SD)
  2. Abbreviations: EC Exercise counseling, NC Nutrition counseling, FBG Fasting blood glucose, LDL Low-density lipoprotein cholesterol, HDL High-density lipoprotein cholesterol, BP Blood pressure, HbA1c Hemoglobin A1c, BMI Body mass index
Back to article page

Pilot and Feasibility Studies

ISSN: 2055-5784